Thread: Covid 19 -
View Single Post
Old 10-08-2020, 04:15 PM   #5153
russellw
Chairman & Administrator
Donating Member3
 
russellw's Avatar
 
Join Date: Dec 2004
Location: 1975
Posts: 106,469
Community Builder: In recognition of those who have helped build the AFF community. - Issue reason: Raptor: For Continued, and prolonged service to the wider Ford Community 
Default Re: Covid 19 -

Quote:
Originally Posted by EgoFG
I have heard anecdotal evidence of people being infected a second time. Young (under 55) people recovering but with significant long term problems.
I tend not to believe until I see some reliable figures.


Does anyone have any statistics of


1) reinfections - requiring inpatient/outpatient treatment both times
2) recovery with life changing long term negative effects

Anecdotes while fun are not things to base life decisions on.
eg Vesna Vulović survived a 10,000 metre fall from a flight - so ... would you choose to jump out of a perfectly functioning plane without a 'chute ??
There isn't a lot of hard data as yet but a couple of studies do provide what insight we have thus far.

What we do know about reinfections:

Detectable IgM and IgG antibodies develop within days to weeks of onset in most but not all infected individuals.

The viral load typically peaks early in the illness and then declines as antibodies develop and antibody titers rise over a 2-3 week period (full article HERE).

The durability of antibodies has yet to be defined. Persistence of up to 40 days from symptom onset has been identified in a Chinese study.

What might help is antibody responses against other human coronaviruses - for example, following infection with SARS, concentrations of IgG remained high for approximately 4-5 months before subsequently declining slowly during the next 2 to 3 years. (Article Link).

There is one small Chinese study using four rhesus macaques where reinfection didn't occur after 30 days but that's far from conclusive and hasn't been peer reviewed.

The claimed Korean and Chinese reinfection cases are still under a question mark, with our own DoH commenting:

It is likely that positive tests soon after recovery represent persisting excretion of viral RNA, and it should be noted that PCR [polymerase chain reaction] tests cannot distinguish between “live” virus and non-infective RNA.

What we do know about longer term health impacts:Is probably best summarised in THIS article from the RACGP.

In short (for those who don;t want to read it).

Those who end up in ICU are almost certainly going to have longer term lung damage and quite possibly cardio-pulmonary issues as well.

Those who get a severe case seem likely to suffer some loss of lung capacity as well as chronic fatigue.

Studies of SARS have shown quite a high level of long term impacts from the disease even for normally healthy people and it's not dissimilar in many ways. (Link to another study).
__________________

__________________________________________________

Observatio Facta Rotae


russellw is offline  
4 users like this post: